pentobarbital will decrease the extent or influence of aripiprazole by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.
pentobarbital will increase effects of ifosfamide by influencing hepatic enzyme CYP2B6 metabolism. Use Warning/Keep track of. Coadministration of ifosfamide with CYP2B6 inducers could improve metabolism of ifosfamide to its metabolite. Watch for greater effects/toxicities if put together with CYP2B6 inducers.
Use Warning/Keep an eye on. CYP3A4 inducers could raise the metabolism of clopidogrel to its Energetic metabolite. Keep track of individuals for probable increase in antiplatelet effects when CYP3A4 inducers are applied together with clopidogrel
pentobarbital will improve the level or impact of ivosidenib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Prevent or Use Alternate Drug. Coadministration of ivosidenib with powerful CYP3A4 inducers lowered ivosidenib plasma concentrations.
pentobarbital will decrease the level or effect of etravirine by influencing hepatic enzyme CYP2C9/ten metabolism. Use Warning/Watch.
pentobarbital will lower the extent or outcome of apremilast by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Avoid or Use Alternate Drug. Coadministration with strong CYP inducers leads to a big lower of systemic exposure of apremilast, which may lead to lack of efficacy
pentobarbital will reduce the extent or influence of netupitant/palonosetron by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Stay away from or Use Alternate Drug. Netupitant is especially metabolized by CYP3A4; stay away from use in clients who're chronically utilizing a robust CYP3A4 inducer
Phenytoin and barbiturate blood amounts need to be monitored extra often if provided concurrently; influence of barbiturates on phenytoin metabolism described to become variable; sodium valproate and valproic acid seem to reduce barbiturate metabolism; check barbiturate blood stages and make correct dosage adjustments as essential
pentobarbital will minimize the level or impact of sunitinib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.
pentobarbital will lessen the extent or effect of diclofenac by affecting hepatic enzyme CYP2C9/ten metabolism. Insignificant/Importance Not known.
pentobarbital will minimize the level or result of terbinafine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.
pentobarbital will minimize the extent or result of ambrisentan by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Importance Unknown.
pentobarbital will reduce the extent or influence of darifenacin by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on.
pentobarbital will lessen the extent or influence here of ramelteon by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Importance Not known.